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Thus, future research in this area needs to focus on such patients. These patients are likely to be younger, so even small increases in the ability to detect deterioration would result in substantial gains in terms of years of life saved. Finally, as scores such as AAM and eCART are used in actual practice, data from patients who reach alert thresholds will be contaminated by clinician treatment in response to alerts.
This will pose challenges to the development, updating and evaluation of predictive models, and future research must begin considering these.